Reactome | NTF3:p-5Y-Ntrk3 homodimer [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-NUL-9036938] NTF3:p-5Y-Ntrk3 homodimer:p-Y-Shc1 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-NUL-9034884] Activated Ntrk3 binds Shc1 - Homo sapiens [Reaction:R-NUL-9603412] Activated Ntrk3 binds PI3K - Homo sapiens [Reaction:R-NUL-9034794] Activated Ntrk3 binds Plcg1 - Homo sapiens [BlackBoxEvent:R-NUL-9603754] PTPRS dephosphorylates Ntrk3 - Gallus gallus
created	[InstanceEdit:9034804] Orlic-Milacic, Marija, 2018-01-11
dbId	9034806
displayName	NTF3:p-5Y-Ntrk3 homodimer [plasma membrane]
hasComponent	[Complex:R-HSA-9025070] NTF3 homodimer [extracellular region] 2 × [EntityWithAccessionedSequence:R-RNO-181845] p-5Y-Ntrk3 [plasma membrane]
inDisease	false
includedLocation	[Compartment:984] extracellular region
isChimeric	true
maxDepth	3
modified	[InstanceEdit:9603929] Orlic-Milacic, Marija, 2018-03-28
name	NTF3:p-5Y-Ntrk3 homodimer
positivelyRegulates	[PositiveRegulation:9036968] Positive regulation by 'NTF3:p-5Y-Ntrk3 homodimer [plasma membrane]'
schemaClass	Complex
species	[Species:48887] Homo sapiens [Species:48895] Rattus norvegicus
stId	R-NUL-9034806

(regulator)	[PositiveRegulation:9036968] Positive regulation by 'NTF3:p-5Y-Ntrk3 homodimer [plasma membrane]'
(hasComponent)	[Complex:R-NUL-9036938] NTF3:p-5Y-Ntrk3 homodimer:p-Y-Shc1 [plasma membrane] [Complex:R-NUL-9034885] NTF3:p-5Y-Ntrk3 homodimer:Shc1 [plasma membrane] [Complex:R-NUL-9603414] NTF3:p-5Y-Ntrk3 homodimer:PI3K [plasma membrane] [Complex:R-NUL-9034826] NTF3:p-5Y-Ntrk3 homodimer:p-4Y-Plcg1 [plasma membrane] [Complex:R-NUL-9034829] NTF3:p-5Y-Ntrk3 homodimer:Plcg1 [plasma membrane] [Complex:R-NUL-9034809] NTF3:p-5Y-Ntrk3 homodimer:Plcg1 [plasma membrane]
(activeUnit)	[CatalystActivity:9603933] protein tyrosine kinase activity of NTF3:p-5Y-Ntrk3 homodimer:Shc1 [plasma membrane] [CatalystActivity:9034827] protein tyrosine kinase activity of NTF3:p-5Y-Ntrk3 homodimer:Plcg1 [plasma membrane]
(input)	[Reaction:R-NUL-9034884] Activated Ntrk3 binds Shc1 [Reaction:R-NUL-9603412] Activated Ntrk3 binds PI3K [Reaction:R-NUL-9034794] Activated Ntrk3 binds Plcg1 [BlackBoxEvent:R-NUL-9603754] PTPRS dephosphorylates Ntrk3