Reactome | Notch4 coactivator complex [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-NUL-9604510] Notch4 coactivator complex:FLT4 gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-NUL-9604511] Notch4 binds FLT4 gene promoter - Mus musculus
created	[InstanceEdit:9013701] Orlic-Milacic, Marija, 2017-07-25
dbId	9013691
displayName	Notch4 coactivator complex [nucleoplasm]
hasComponent	[CandidateSet:R-HSA-212357] MAML [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9013692] NICD4 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-3008668] RBPJ [nucleoplasm]
inDisease	false
isChimeric	true
literatureReference	[LiteratureReference:9013630] Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling
maxDepth	3
modified	[InstanceEdit:9013721] Orlic-Milacic, Marija, 2017-07-25
name	Notch4 coactivator complex
positivelyRegulates	[PositiveRegulation:9604462] Positive regulation by 'Notch4 coactivator complex [nucleoplasm]' [PositiveGeneExpressionRegulation:9604518] Positive gene expression regulation by 'Notch4 coactivator complex [nucleoplasm]'
producedByEvent	[Reaction:R-NUL-9013699] NICD4 binds RBPJ and MAML in the nucleus - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stId	R-NUL-9013691

(regulator)	[PositiveRegulation:9604462] Positive regulation by 'Notch4 coactivator complex [nucleoplasm]' [PositiveGeneExpressionRegulation:9604518] Positive gene expression regulation by 'Notch4 coactivator complex [nucleoplasm]'
(hasComponent)	[Complex:R-NUL-9604510] Notch4 coactivator complex:FLT4 gene [nucleoplasm]
(input)	[Reaction:R-NUL-9604511] Notch4 binds FLT4 gene promoter
(output)	[Reaction:R-NUL-9013699] NICD4 binds RBPJ and MAML in the nucleus