Reactome | RFzd binds trimeric G-proteins

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RFzd binds trimeric G-proteins Show undefined attributes

authored	[InstanceEdit:4518594] Rothfels, K, 2013-09-03
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:4551538] Rothfels, K, 2013-09-13
dbId	4551534
displayName	RFzd binds trimeric G-proteins
edited	[InstanceEdit:4663813] Matthews, L, 2013-10-07
input	[EntityWithAccessionedSequence:R-RNO-3965363] Fzd2 [plasma membrane] [Complex:R-MMU-4551535] heterotrimeric G-protein(o/t2) (inactive) [cytosol] [EntityWithAccessionedSequence:R-XLA-3965359] Wnt5a [extracellular region]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3965291] Activation of a frizzled-2/beta-adrenergic receptor chimera promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via Galphao and Galphat [LiteratureReference:517384] Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RFzd binds trimeric G-proteins
orthologousEvent	[Reaction:R-HSA-3965441] FZD recruits trimeric G-proteins - Homo sapiens
output	[Complex:R-NUL-4551537] XWnt5a:RFzd2:G-protein(alpha o/t2) (inactive) [plasma membrane]
releaseDate	2013-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5099870] Kikuchi, Akira, 2013-11-12
schemaClass	Reaction
species	[Species:48892] Mus musculus [Species:48895] Rattus norvegicus [Species:51320] Xenopus laevis
stId	R-NUL-4551534
summation	[Summation:4551531] Stimulation of mouse teratocarcinoma cells expressing rat Fz...

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