Reactome | Dystroglycan bind Laminins and Dystrophin

Schema > Reaction > Entries

authored	[InstanceEdit:2426268] Jupe, S, 2012-07-31
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:2426629] Jupe, S, 2012-08-08
dbId	2426616
displayName	Dystroglycan bind Laminins and Dystrophin
edited	[InstanceEdit:3318356] Jupe, S, 2013-04-26
input	[Complex:R-OCU-2426648] Dystroglycan [plasma membrane] [EntityWithAccessionedSequence:R-OCU-2426605] Dystrophin [cytosol] [DefinedSet:R-MMU-2426641] Laminins [extracellular region]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2328092] A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin [LiteratureReference:2426614] Dystroglycan is a binding protein of laminin and merosin in peripheral nerve
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Dystroglycan bind Laminins and Dystrophin
orthologousEvent	[Reaction:R-HSA-2328129] Dystroglycan binds Laminins and Dystrophin - Homo sapiens
output	[Complex:R-NUL-2426661] Dystrophin:Dystroglycan:Laminins [plasma membrane]
releaseDate	2013-06-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3597676] Ricard-Blum, Sylvie, 2013-05-22
schemaClass	Reaction
species	[Species:48892] Mus musculus [Species:49130] Oryctolagus cuniculus
stId	R-NUL-2426616
summation	[Summation:2426652] Dystroglycan (DG) is a cell-surface laminin receptor. In ske...

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