Reactome | Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex

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Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex Show undefined attributes

authored	[InstanceEdit:386950] Williams, MG, 2006-07-26 16:49:12
catalystActivity	[CatalystActivity:208882] protein serine/threonine kinase activity of CKIgamma [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:205655] Williams, MG, 2006-10-24 12:52:33
dbId	209104
displayName	Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex
figure	[Figure:210816] /figures/CDrosWing16a.jpg
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-NUL-9608501] Wnt1:Frizzled1:phospho LRP6:CKIgamma [plasma membrane]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:208206] Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction [LiteratureReference:208343] A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex
orthologousEvent	[Reaction:R-DME-209135] GISH further phosphorylates ARR in the receptor complex - Drosophila melanogaster
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-NUL-206831] Wnt1:Frizzled1:phospho (3 sites) LRP6:CKIgamma [plasma membrane]
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:386952] Nusse, Roel, 2008-01-19
schemaClass	Reaction
species	[Species:48887] Homo sapiens [Species:205621] Xenopus tropicalis
stId	R-NUL-209104
summation	[Summation:9616753] Frog CKIgamma further phosphorylates Human LRP6 in the recep...
updateTrackers	[UpdateTracker:9779389] Update Tracker - [Reaction:209104] Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex - v65:[add_removeInput] [UpdateTracker:9779205] Update Tracker - [Reaction:209104] Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex - v66:[addSummation]

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[UpdateTracker:9779389] Update Tracker - [Reaction:209104] Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex - v65:[add_removeInput]
[UpdateTracker:9779205] Update Tracker - [Reaction:209104] Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex - v66:[addSummation]

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