Reactome | Plcg1 binds P-ERBB2:P-EGFR

Schema > Reaction > Entries

authored	[InstanceEdit:1972351] Orlic-Milacic, M, 2011-11-04
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:1251935] Orlic-Milacic, Marija, 2011-04-25
dbId	1251923
displayName	Plcg1 binds P-ERBB2:P-EGFR
edited	[InstanceEdit:1972361] Matthews, L, 2011-11-07
input	[Complex:R-HSA-1248703] EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-1251925] Plcg1 [plasma membrane]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1251927] The erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potency
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Plcg1 binds P-ERBB2:P-EGFR
orthologousEvent	[Reaction:R-HSA-1251944] PLCG1 binds to p-ERBB2:p-EGFR - Homo sapiens
output	[Complex:R-NUL-1251930] Plcg1:P-ERBB2:P-EGFR [plasma membrane]
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1972347] Neckers, LM, 2011-11-11 [InstanceEdit:1972346] Xu, W, 2011-11-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stId	R-NUL-1251923
summation	[Summation:1251938] Mouse phospholipase C gamma 1 is phosphorylated by human rec...

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