Reactome | ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10097927] ubiquitin-protein transferase activity of ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-MMU-9948301] ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10097926
displayName	ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol]
hasComponent	[Complex:R-MMU-9954725] 80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] [Complex:R-MMU-8953915] Ub:UBE2D1,2,3 [cytosol] [EntityWithAccessionedSequence:R-MMU-9948290] Znf598 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9948313] ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol] - Homo sapiens
maxDepth	7
name	ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide
producedByEvent	[Reaction:R-MMU-9948317] ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-9948313
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-9948301] ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit
(physicalEntity)	[CatalystActivity:10097927] ubiquitin-protein transferase activity of ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol]
(output)	[Reaction:R-MMU-9948317] ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome
(inferredTo)	[Complex:R-HSA-9948313] ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol]

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