Reactome | Phosphorylated Bmal1:Clock positively regulates expression of Nr1d1

Schema > BlackBoxEvent > Entries

Phosphorylated Bmal1:Clock positively regulates expression of Nr1d1 Show undefined attributes

authored	[InstanceEdit:9926597] May, Bruce, 2024-11-01
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9926614] May, Bruce, 2024-11-01
dbId	9926623
displayName	Phosphorylated Bmal1:Clock positively regulates expression of Nr1d1
edited	[InstanceEdit:9926597] May, Bruce, 2024-11-01
input	[EntityWithAccessionedSequence:R-MMU-5663171] Nr1d1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9926652] Chronobiological analysis of circadian patterns in transcription of seven key clock genes in six peripheral tissues in mice [LiteratureReference:9929961] Relationship between circadian oscillations of Rev-erbalpha expression and intracellular levels of its ligand, heme [LiteratureReference:9930010] Rev-erbalpha gene expression in the mouse brain with special emphasis on its circadian profiles in the suprachiasmatic nucleus [LiteratureReference:9930004] Transcriptional oscillation of canonical clock genes in mouse peripheral tissues [LiteratureReference:1368121] Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism
maxDepth	1
modified	[InstanceEdit:9938697] May, Bruce, 2025-02-18
name	Phosphorylated Bmal1:Clock positively regulates expression of Nr1d1
orthologousEvent	[BlackBoxEvent:R-HSA-9923018] Phosphorylated BMAL1:CLOCK positively regulates expression of NR1D1 (REV-ERBA) - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-508732] Nr1d1 [nucleoplasm]
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[PositiveGeneExpressionRegulation:9926649] Positive gene expression regulation by 'p-S97-Bmal1:p-T451,T461-Clock:Nr1d1 gene [nucleoplasm]'
regulationReference	[RegulationReference:9926650] Positive gene expression regulation by 'p-S97-Bmal1:p-T451,T461-Clock:Nr1d1 gene [nucleoplasm]' The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938389] Sancar, Aziz, 2025-02-14 [InstanceEdit:9938694] Albrecht, Urs, 2025-02-18
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9926623
summation	[Summation:9929990] Phosphorylated Bmal1:Clock heterodimers bound to the promote...

Cite Us!