Reactome | Autoproteolysis of DAG1 to alpha and beta chains

Schema > Reaction > Entries

Autoproteolysis of DAG1 to alpha and beta chains Show undefined attributes

catalystActivity	[CatalystActivity:10096217] serine-type endopeptidase activity of DAG1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10096219
displayName	Autoproteolysis of DAG1 to alpha and beta chains
eventOf	[Pathway:R-MMU-9913351] Formation of the dystrophin-glycoprotein complex (DGC) - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-MMU-9913337] DAG1(30-653) and DAG1(654-895) translocate to the Golgi - Mus musculus [Reaction:R-MMU-5615637] POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) - Mus musculus
inferredFrom	[Reaction:R-HSA-9913329] Autoproteolysis of DAG1 to alpha and beta chains - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-9913254] Dag1 [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Autoproteolysis of DAG1 to alpha and beta chains
output	[EntityWithAccessionedSequence:R-MMU-8931890] Dag1 [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:R-MMU-9913257] Dag1 [endoplasmic reticulum membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9913329
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9913351] Formation of the dystrophin-glycoprotein complex (DGC)
(precedingEvent)	[BlackBoxEvent:R-MMU-9913337] DAG1(30-653) and DAG1(654-895) translocate to the Golgi [Reaction:R-MMU-5615637] POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653)
(inferredTo)	[Reaction:R-HSA-9913329] Autoproteolysis of DAG1 to alpha and beta chains