Reactome | ATP:P2rx7 trimer:Panx1 heptamer [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9907483] extracellularly ATP-gated monoatomic cation channel activity of ATP:P2rx7 trimer:Panx1 heptamer [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9907471] May, Bruce, 2024-04-10
dbId	9907470
displayName	ATP:P2rx7 trimer:Panx1 heptamer [plasma membrane]
hasComponent	[Complex:R-MMU-9907456] ATP:P2rx7 trimer [plasma membrane] [Complex:R-MMU-9857678] Panx1 heptamer [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
isChimeric	false
literatureReference	[LiteratureReference:9905957] P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes [LiteratureReference:9905971] Potential role for a specialized ?₃ integrin-based structure on osteocyte processes in bone mechanosensation
maxDepth	4
name	ATP:P2rx7 trimer:Panx1 heptamer
producedByEvent	[Reaction:R-MMU-9907464] ATP binds P2rx7 in P2rx7 trimer:Panx1 heptamer - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-9907470

(physicalEntity)	[CatalystActivity:9907483] extracellularly ATP-gated monoatomic cation channel activity of ATP:P2rx7 trimer:Panx1 heptamer [plasma membrane]
(output)	[Reaction:R-MMU-9907464] ATP binds P2rx7 in P2rx7 trimer:Panx1 heptamer

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