Reactome | A4GALT transfers galactose to LacCer

Schema > Reaction > Entries

A4GALT transfers galactose to LacCer Show undefined attributes

catalystActivity	[CatalystActivity:10095164] lactosylceramide 4-alpha-galactosyltransferase activity of A4GALT [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10095166
displayName	A4GALT transfers galactose to LacCer
eventOf	[Pathway:R-MMU-9840309] Glycosphingolipid biosynthesis - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-8878914] B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer - Mus musculus
inferredFrom	[Reaction:R-HSA-9846477] A4GALT transfers galactose to LacCer - Homo sapiens
input	[SimpleEntity:R-ALL-9844874] LacCer-d18 [Golgi membrane] [SimpleEntity:R-ALL-735682] UDP-Gal [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	A4GALT transfers galactose to LacCer
output	[SimpleEntity:R-ALL-8879102] Gb3Cer [Golgi membrane] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [SimpleEntity:R-ALL-205687] UDP [Golgi lumen]
precedingEvent	[Reaction:R-MMU-9851347] B4GALT5/6 transfer Gal to GlcCer - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9846477
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9840309] Glycosphingolipid biosynthesis
(precedingEvent)	[Reaction:R-MMU-8878914] B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer
(inferredTo)	[Reaction:R-HSA-9846477] A4GALT transfers galactose to LacCer

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