Reactome | Ebf2 binds target gene loci

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Ebf2 binds target gene loci Show undefined attributes

authored	[InstanceEdit:9844988] Orlic-Milacic, Marija, 2023-09-25
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9844451] Orlic-Milacic, Marija, 2023-09-18
dbId	9844452
displayName	Ebf2 binds target gene loci
edited	[InstanceEdit:9855181] Orlic-Milacic, Marija, 2023-11-29
input	8 × [DefinedSet:R-MMU-9854592] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu [nucleoplasm] [CandidateSet:R-MMU-9854594] Ppara gene, Prdm16 gene, Ucp1 gene, (Cidea gene, Cox7a1 gene, Dio2 gene, Elovl3 gene, Ppargc1a gene) [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9844612] EBF2 determines and maintains brown adipocyte identity [LiteratureReference:9844609] EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex [LiteratureReference:9844613] Ebf2 is a selective marker of brown and beige adipogenic precursor cells [LiteratureReference:9844394] ZFP423 controls EBF2 coactivator recruitment and PPAR? occupancy to determine the thermogenic plasticity of adipocytes [LiteratureReference:9844390] Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program [LiteratureReference:9844687] BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning [LiteratureReference:9844362] A long noncoding RNA transcriptional regulatory circuit drives thermogenic adipocyte differentiation [LiteratureReference:9844400] Conserved function of the long noncoding RNA Blnc1 in brown adipocyte differentiation [LiteratureReference:9844614] EBF2 promotes the recruitment of beige adipocytes in white adipose tissue [LiteratureReference:9844565] Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis [LiteratureReference:9844640] Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism [LiteratureReference:9844638] Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning
maxDepth	1
modified	[InstanceEdit:9855222] Orlic-Milacic, Marija, 2023-11-29
name	Ebf2 binds target gene loci
orthologousEvent	[Reaction:R-HSA-9844366] EBF2 binds target gene loci - Homo sapiens
output	[CandidateSet:R-MMU-9854763] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu:Ppara gene, Prdm16 gene, Ucp1 gene, (Cidea gene, Cox7a1 gene, Dio2 gene, Elovl3 gene, Ppargc1a gene) [nucleoplasm]
releaseDate	2024-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9854531] Chun, Tae-Hwa, 2023-11-29
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9844452
summation	[Summation:9844897] In mouse brown and beige adipocyte lineages Ebf2 transcripti...

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