Reactome | LTK binds ALKAL ligand

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10094609
displayName	LTK binds ALKAL ligand
eventOf	[Pathway:R-MMU-9842663] Signaling by LTK - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-9842648] Autophosphorylation of LTK dimer:ALKAL1,2 - Mus musculus
inferredFrom	[Reaction:R-HSA-9842660] LTK binds ALKAL ligand - Homo sapiens
input	[DefinedSet:R-MMU-9842609] ALKAL1,2 [extracellular region] 2 × [EntityWithAccessionedSequence:R-MMU-9842564] LTK [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	LTK binds ALKAL ligand
output	[Complex:R-MMU-9842594] LTK dimer:ALKAL1,2 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9842660
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-9842663] Signaling by LTK
(precedingEvent)	[Reaction:R-MMU-9842648] Autophosphorylation of LTK dimer:ALKAL1,2
(inferredTo)	[Reaction:R-HSA-9842660] LTK binds ALKAL ligand

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