Reactome | Expression of Lhx1 in the nephric duct

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Expression of Lhx1 in the nephric duct Show undefined attributes

authored	[InstanceEdit:9830357] May, Bruce, 2023-03-09
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9830452] May, Bruce, 2023-03-12
dbId	9830429
displayName	Expression of Lhx1 in the nephric duct
edited	[InstanceEdit:9830357] May, Bruce, 2023-03-09
input	[EntityWithAccessionedSequence:R-MMU-9761201] Lhx1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9774508] Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms [LiteratureReference:9825078] Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis [LiteratureReference:9830355] Expression patterns of the murine LIM class homeobox gene lim1 in the developing brain and excretory system [LiteratureReference:9792537] Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development [LiteratureReference:9774609] Requirement for Lim1 in head-organizer function [LiteratureReference:9761190] Lim1 activity is required for intermediate mesoderm differentiation in the mouse embryo [LiteratureReference:9830441] PAX2 is dispensable for in vitro nephron formation from human induced pluripotent stem cells [LiteratureReference:9761194] Nephric lineage specification by Pax2 and Pax8
maxDepth	1
modified	[InstanceEdit:9851767] May, Bruce, 2023-10-31
name	Expression of Lhx1 in the nephric duct
orthologousEvent	[BlackBoxEvent:R-HSA-9830356] Expression of LHX1 (LIM1) in the nephric duct - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-9761161] Lhx1 [nucleoplasm]
regulatedBy	[PositiveGeneExpressionRegulation:9830469] Positive gene expression regulation by 'Pax8 [nucleoplasm]' [PositiveGeneExpressionRegulation:9774492] Positive gene expression regulation by 'Pax2:Lhx1 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9830495] Positive gene expression regulation by 'Gata3:Pax2:Lhx1 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9830499] Positive gene expression regulation by 'Emx2 [nucleoplasm]'
regulationReference	[RegulationReference:9830464] Positive gene expression regulation by 'Pax8 [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis [RegulationReference:9774493] Positive gene expression regulation by 'Pax2:Lhx1 gene [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis [RegulationReference:9830490] Positive gene expression regulation by 'Gata3:Pax2:Lhx1 gene [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis [RegulationReference:9830497] Positive gene expression regulation by 'Emx2 [nucleoplasm]' Defects of urogenital development in mice lacking Emx2
releaseDate	2023-12-06
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9830429
summation	[Summation:9831424] Lhx1 (Lim1) is initially expressed throughout the intermedia...

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