Reactome | Lef1:Ctnnb1, Nicd (Notch), and Tbx6 bind the Hes7 gene in presomitic mesoderm

Schema > Reaction > Entries

Lef1:Ctnnb1, Nicd (Notch), and Tbx6 bind the Hes7 gene in presomitic mesoderm Show undefined attributes

authored	[InstanceEdit:9820524] Chalamalasetty, Ravindra B, 2022-11-09 [InstanceEdit:9820530] Yamaguchi, Terry P, 2022-11-09
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9824212] May, Bruce, 2023-01-18
dbId	9824206
displayName	Lef1:Ctnnb1, Nicd (Notch), and Tbx6 bind the Hes7 gene in presomitic mesoderm
edited	[InstanceEdit:9824085] May, Bruce, 2023-01-14
input	[EntityWithAccessionedSequence:R-MMU-9824204] Hes7 gene [nucleoplasm] [Complex:R-MMU-9735207] Lef1:Ctnnb1 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-189582] nicd1 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-189590] Rbpj [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9793381] Tbx6 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9824265] Control of Hes7 expression by Tbx6, the Wnt pathway and the chemical Gsk3 inhibitor LiCl in the mouse segmentation clock [LiteratureReference:9824226] Presomitic mesoderm-specific expression of the transcriptional repressor Hes7 is controlled by E-box, T-box, and Notch signaling pathways
maxDepth	1
modified	[InstanceEdit:9835282] May, Bruce, 2023-05-12
name	Lef1:Ctnnb1, Nicd (Notch), and Tbx6 bind the Hes7 gene in presomitic mesoderm
orthologousEvent	[Reaction:R-HSA-9824266] LEF1:CTNNB1, NICD1 (NOTCH1) and TBX6 bind the HES7 gene in presomitic mesoderm - Homo sapiens
output	[Complex:R-MMU-9824239] Lef1:Ctnnb1:Tbx6:Rbpj:Nicd:Hes7 gene [nucleoplasm]
releaseDate	2023-06-07
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9835280] May, Bruce, 2023-05-12
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9824206
summation	[Summation:9824246] Tbx6 binds two sites approximately 1.3 kb upstream of the tr...

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