Reactome | ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans

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ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans Show undefined attributes

catalystActivity	[CatalystActivity:10025449] beta-galactoside alpha-2,6-sialyltransferase activity of ST6GAL1 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10025451
displayName	ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans
eventOf	[Pathway:R-MMU-975577] N-Glycan antennae elongation - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-975902] ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans - Homo sapiens
input	[SimpleEntity:R-ALL-975925] Neu5Ac [Golgi lumen] [SimpleEntity:R-ALL-975910] NGP [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans Addition of alpha-2,6-sialic acid to terminal galactose of N-glycans by ST6GAL1
output	[OtherEntity:R-ALL-981615] Glycoprotein-Neu5Ac [Golgi lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-975902
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-975577] N-Glycan antennae elongation
(inferredTo)	[Reaction:R-HSA-975902] ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans

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