Reactome | p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene

Schema > Reaction > Entries

p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene Show undefined attributes

authored	[InstanceEdit:9756753] May, Bruce, 2021-10-18
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9756953] May, Bruce, 2021-10-22
dbId	9756964
displayName	p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene
edited	[InstanceEdit:9756753] May, Bruce, 2021-10-18
input	[Complex:R-MMU-9756959] Foxh1:Smad3:Gsc gene [nucleoplasm] [Complex:R-MMU-9760357] p-2S-Smad2,3:Trim33 [nucleoplasm] [Complex:R-MMU-9625501] p-2S-Smad2/3:Smad4 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9756934] Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-? signaling [LiteratureReference:9794953] The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells [LiteratureReference:9756932] A poised chromatin platform for TGF-? access to master regulators [LiteratureReference:2975839] Pluripotency factors regulate definitive endoderm specification through eomesodermin [LiteratureReference:9754504] Eomes and Brachyury control pluripotency exit and germ-layer segregation by changing the chromatin state
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene
orthologousEvent	[Reaction:R-HSA-9756948] p-2S-SMAD2,3:SMAD4, p-2S-SMAD2,3:TRIM33, CTNNB1, EOMES, and TBPL2 bind FOXH1:SMAD3:GSC gene - Homo sapiens
output	[Complex:R-MMU-9756960] p-2S-Smad2,3:Smad4:p-2S-Smad2,3:Trim33:Foxh1:Smad3:Gsc gene [nucleoplasm]
releaseDate	2022-06-09
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9773645] Tam, Patrick P L, 2022-05-08 [InstanceEdit:9794593] Probst, Simone, 2022-07-18 [InstanceEdit:9796183] Zissel, Lea, 2022-07-18 [InstanceEdit:9796182] Salehin, Nazmus, 2022-05-08
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9756964
summation	[Summation:9760361] In mesendoderm progenitors, Foxh1 and Smad3 are pre-bound to...
updateTrackers	[UpdateTracker:9847065] Update Tracker - [Reaction:9756964] p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene - v82:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9847065] Update Tracker - [Reaction:9756964] p-2S-Smad2,3:Smad4 binds Foxh1:Smad3:Gsc gene - v82:[addLiteratureReference, modifyText]