Reactome | BCMO1:Fe2+ cleaves betaC to atRAL

Schema > Reaction > Entries

BCMO1:Fe2+ cleaves betaC to atRAL Show undefined attributes

catalystActivity	[CatalystActivity:10025418] beta-carotene 15,15'-dioxygenase activity of BCMO1:Fe2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10025420
displayName	BCMO1:Fe2+ cleaves betaC to atRAL
eventOf	[Pathway:R-MMU-975634] Retinoid metabolism and transport - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-2399913] atRAL binds to RBP2 - Mus musculus
inferredFrom	[Reaction:R-HSA-975635] BCMO1:Fe2+ cleaves betaC to atRAL - Homo sapiens
input	[SimpleEntity:R-ALL-975643] betaC [plasma membrane] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	BCMO1:Fe2+ cleaves betaC to atRAL Oxidative cleavage of beta-carotene to all-trans-retinal
output	2 × [SimpleEntity:R-ALL-975622] atRAL [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-975635
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-975634] Retinoid metabolism and transport
(precedingEvent)	[Reaction:R-MMU-2399913] atRAL binds to RBP2
(inferredTo)	[Reaction:R-HSA-975635] BCMO1:Fe2+ cleaves betaC to atRAL

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