Reactome | GLP1R binds GLP1R agonists

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10091606
displayName	GLP1R binds GLP1R agonists
eventOf	[Pathway:R-MMU-381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9728664] GLP1R binds GLP1R agonists - Homo sapiens
input	[CandidateSet:R-ALL-9728630] GLP1R agonists [extracellular region] [Complex:R-MMU-422314] GLP1R:Heterotrimeric G(s):GDP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	GLP1R binds GLP1R agonists
output	[Complex:R-MMU-9728662] GLP1R:GLP1R agonists [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9728664
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
(inferredTo)	[Reaction:R-HSA-9728664] GLP1R binds GLP1R agonists