Reactome | IgE binds FCERI

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10091519
displayName	IgE binds FCERI
eventOf	[Pathway:R-MMU-2454202] Fc epsilon receptor (FCERI) signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-MMU-2454192] Allergen dependent IgE bound FCERI aggregation - Mus musculus
inferredFrom	[Reaction:R-HSA-9725206] IgE binds FCERI - Homo sapiens
input	[Complex:R-MMU-2454198] FCERI [plasma membrane] [Complex:R-MMU-1591211] IgE [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	IgE binds FCERI
output	[Complex:R-MMU-2454224] FCERI:IgE [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9725206
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-2454202] Fc epsilon receptor (FCERI) signaling
(precedingEvent)	[BlackBoxEvent:R-MMU-2454192] Allergen dependent IgE bound FCERI aggregation
(inferredTo)	[Reaction:R-HSA-9725206] IgE binds FCERI