Reactome | IFNG dimer binds IFNG inhibitors

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10089965
displayName	IFNG dimer binds IFNG inhibitors
eventOf	[Pathway:R-MMU-877300] Interferon gamma signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9689680] IFNG dimer binds IFNG inhibitors - Homo sapiens
input	[Complex:R-MMU-873823] IFNG dimer [extracellular region] [DefinedSet:R-ALL-9689692] IFNG inhibitors [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	IFNG dimer binds IFNG inhibitors
output	[Complex:R-MMU-9689688] IFNG dimer:IFNG inhibitors [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9689680
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-877300] Interferon gamma signaling
(inferredTo)	[Reaction:R-HSA-9689680] IFNG dimer binds IFNG inhibitors

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