Reactome | Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds Stat1,3,5

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Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds Stat1,3,5 Show undefined attributes

authored	[InstanceEdit:9674838] May, Bruce, 2020-01-27
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9674890] May, Bruce, 2020-01-29
dbId	9674959
displayName	Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds Stat1,3,5
edited	[InstanceEdit:9674838] May, Bruce, 2020-01-27
input	[Complex:R-MMU-9676066] Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 [plasma membrane] [DefinedSet:R-MMU-9674895] Stat1,3,5 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9674904] Tyrosine residues in the granulocyte colony-stimulating factor (G-CSF) receptor mediate G-CSF-induced differentiation of murine myeloid leukemic (M1) cells [LiteratureReference:9674891] The membrane-distal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3 but not STAT1 homodimer formation [LiteratureReference:9674953] STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: role for the cyclin-dependent kinase inhibitor p27(Kip1) [LiteratureReference:9674906] Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells [LiteratureReference:9674963] Identification of a novel Stat3 recruitment and activation motif within the granulocyte colony-stimulating factor receptor
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds Stat1,3,5
orthologousEvent	[Reaction:R-HSA-9674562] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds STAT1,3,5 - Homo sapiens
output	[Complex:R-MMU-9674981] Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2:Stat1,3,5 [plasma membrane]
releaseDate	2021-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9709304] Touw, Ivo P, 2020-12-12
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9674959
summation	[Summation:9677139] The Stat proteins Stat1 (de Koning et al 1996, Nicholson et ...

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