Reactome | p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2

Schema > Reaction > Entries

p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2 Show undefined attributes

authored	[InstanceEdit:9674838] May, Bruce, 2020-01-27
catalystActivity	[CatalystActivity:9674918] protein tyrosine kinase activity of Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9674890] May, Bruce, 2020-01-29
dbId	9674921
displayName	p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2
edited	[InstanceEdit:9674838] May, Bruce, 2020-01-27
input	8 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-MMU-9674961] Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9674955] Unidirectional cross-phosphorylation between the granulocyte colony-stimulating factor and interleukin 3 receptors [LiteratureReference:9674969] Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2
orthologousEvent	[Reaction:R-HSA-9674558] p-Y-JAK1 phosphorylates CSF3R in CSF3 dimer:2xCSF3R:LYN:p-Y-JAK1 - Homo sapiens
output	8 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-MMU-9674894] Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1 [plasma membrane]
releaseDate	2021-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9709304] Touw, Ivo P, 2020-12-12
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9674921
summation	[Summation:9677137] The cytosolic domain of Csf3r is phosphorylated (Pan et al. ...

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