Reactome | Factor IXa binds protein S

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Factor IXa binds protein S Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10089583
displayName	Factor IXa binds protein S
eventOf	[Pathway:R-MMU-9769739] Regulation of clotting cascade - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:1221431] negative regulation of blood coagulation, intrinsic pathway
inferredFrom	[Reaction:R-HSA-9669959] Factor IXa binds protein S - Homo sapiens
input	[Complex:R-MMU-158392] factor VIIIa:factor IXa [plasma membrane] [EntityWithAccessionedSequence:R-MMU-202772] Pros1 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Factor IXa binds protein S FIX binds PROS1
output	[Complex:R-MMU-9669957] FVIIIa:FIXa:PROS1 [plasma membrane]
precedingEvent	[Reaction:R-MMU-481007] Exocytosis of platelet alpha granule contents - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9669959
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9769739] Regulation of clotting cascade
(inferredTo)	[Reaction:R-HSA-9669959] Factor IXa binds protein S

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