Reactome | RAS:GTP binds PI3K

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10089334
displayName	RAS:GTP binds PI3K
eventOf	[Pathway:R-MMU-5673001] RAF/MAP kinase cascade - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9658253] RAS:GTP binds PI3K - Homo sapiens
input	[Complex:R-MMU-109783] p21 RAS:GTP [plasma membrane] [Complex:R-MMU-74693] PI3K [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RAS:GTP binds PI3K
output	[Complex:R-MMU-9658249] p21 RAS:GTP:PI3K [plasma membrane]
precedingEvent	[Reaction:R-MMU-5672965] RAS GEFs promote RAS nucleotide exchange - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9658253
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-5673001] RAF/MAP kinase cascade
(inferredTo)	[Reaction:R-HSA-9658253] RAS:GTP binds PI3K

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