Reactome | Hdac1:Rbl2:E2f4,E2f5:Tfdp1,Tfdp2; Hdac1:Rbl1:E2f4:Tfdp1,Tfdp2:E2f1 gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9625071] Orlic-Milacic, Marija, 2018-10-18
dbId	9625072
deleted	[Deleted:9625077] Deletion of instance: 9608398
displayName	Hdac1:Rbl2:E2f4,E2f5:Tfdp1,Tfdp2; Hdac1:Rbl1:E2f4:Tfdp1,Tfdp2:E2f1 gene [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-MMU-8978988] E2f1 gene [nucleoplasm] [DefinedSet:R-MMU-8978956] Hdac1:Rbl2:E2f4,E2f5:Tfdp1,Tfdp2; Hdac1:Rbl1:E2f4:Tfdp1,Tfdp2 [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:1362298] E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
maxDepth	6
name	Hdac1:Rbl2:E2f4,E2f5:Tfdp1,Tfdp2; Hdac1:Rbl1:E2f4:Tfdp1,Tfdp2:E2f1 gene
negativelyRegulates	[NegativeGeneExpressionRegulation:R-MMU-8979011] Negative gene expression regulation by 'Hdac1:Rbl2:E2f4,E2f5:Tfdp1,Tfdp2; Hdac1:Rbl1:E2f4:Tfdp1,Tfdp2:E2f1 gene [nucleoplasm]'
producedByEvent	[Reaction:R-MMU-8978989] The complex of Hdac1, Rbl1 and E2f4 or Hdac1, Rbl2 and E2f4 or E2f5 binds E2f1 gene promoter - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-9625072

(replacementInstances)	[Deleted:9625077] Deletion of instance: 9608398
(regulator)	[NegativeGeneExpressionRegulation:R-MMU-8979011] Negative gene expression regulation by 'Hdac1:Rbl2:E2f4,E2f5:Tfdp1,Tfdp2; Hdac1:Rbl1:E2f4:Tfdp1,Tfdp2:E2f1 gene [nucleoplasm]'
(output)	[Reaction:R-MMU-8978989] The complex of Hdac1, Rbl1 and E2f4 or Hdac1, Rbl2 and E2f4 or E2f5 binds E2f1 gene promoter

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