Reactome | RAP1:GTP:activated BRAF dimer [endosome membrane]

Schema > Complex > Entries

compartment	[Compartment:74700] endosome membrane
componentOf	[Complex:R-MMU-9610134] RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9610152] Activated BRAF recruits MAP2Ks and MAPKs to the endosome - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10087786
displayName	RAP1:GTP:activated BRAF dimer [endosome membrane]
hasComponent	2 × [Complex:R-MMU-9610128] p-S445,T599,T602,S729 B-Raf complex [cytosol] [Complex:R-MMU-190069] RAP1:GTP [endosome membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-9610130] RAP1:GTP:activated BRAF dimer [endosome membrane] - Homo sapiens
maxDepth	3
name	RAP1:GTP:activated BRAF dimer
producedByEvent	[BlackBoxEvent:R-MMU-9610154] Dissociation of phosphorylated MAP2Ks and MAPKs - Mus musculus [Reaction:R-MMU-9610163] BRAF autophosphorylates downstream of RAP1 and NGF - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-9610130
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-MMU-9610154] Dissociation of phosphorylated MAP2Ks and MAPKs [Reaction:R-MMU-9610163] BRAF autophosphorylates downstream of RAP1 and NGF
(input)	[Reaction:R-MMU-9610152] Activated BRAF recruits MAP2Ks and MAPKs to the endosome
(hasComponent)	[Complex:R-MMU-9610134] RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] [Complex:R-MMU-9610136] RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] [Complex:R-MMU-9610140] RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane]
(inferredTo)	[Complex:R-HSA-9610130] RAP1:GTP:activated BRAF dimer [endosome membrane]