Reactome | Active Flt3 binds Hck

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9634693] Varusai, Thawfeek, 2019-01-14
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9609273] Varusai, Thawfeek, 2018-05-21
dbId	9609272
displayName	Active Flt3 binds Hck
edited	[InstanceEdit:9634693] Varusai, Thawfeek, 2019-01-14
input	[Complex:R-MMU-9604748] Active Flt3 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-9609278] Hck [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9604777] Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2 [LiteratureReference:9609283] Src family tyrosine kinases phosphorylate Flt3 on juxtamembrane tyrosines and interfere with receptor maturation in a kinase-dependent manner
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Active Flt3 binds Hck
orthologousEvent	[BlackBoxEvent:R-HSA-9609274] Active FLT3 binds HCK - Homo sapiens
output	[Complex:R-MMU-9609276] Active Flt3: Hck [plasma membrane]
releaseDate	2019-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9645124] Traer, Elie, 2019-05-03 [InstanceEdit:9646275] Joshi, Sunil, 2019-05-21
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9609272
summation	[Summation:9609277] Feline McDonough Sarcoma-like tyrosine kinase (Flt3) is a me...

Cite Us!