Reactome | TRAF6:hp-IRAK1:Pellino [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10022872] ubiquitin-ubiquitin ligase activity of p-Pellino:hp-IRAK1:TRAF6 [plasma membrane] [CatalystActivity:10022867] protein kinase activity of TRAF6:hp-IRAK1:Pellino [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-MMU-937050] Pellino ubiquitinates hp-IRAK1 - Mus musculus [Reaction:R-MMU-937034] IRAK1 phosphorylates Pellino - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10022866
displayName	TRAF6:hp-IRAK1:Pellino [plasma membrane]
hasComponent	[CandidateSet:R-MMU-450819] p-Pellino-1,2,(3) [cytosol] [Complex:R-MMU-937036] TRAF6:hp-IRAK1 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-937040] p-Pellino:hp-IRAK1:TRAF6 [plasma membrane] - Homo sapiens [Complex:R-HSA-937020] TRAF6:hp-IRAK1:Pellino [plasma membrane] - Homo sapiens
maxDepth	3
name	TRAF6:hp-IRAK1:Pellino
producedByEvent	[Reaction:R-MMU-937034] IRAK1 phosphorylates Pellino - Mus musculus [Reaction:R-MMU-937044] Pellino binds hp-IRAK1:TRAF6 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-937020
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-937050] Pellino ubiquitinates hp-IRAK1 [Reaction:R-MMU-937034] IRAK1 phosphorylates Pellino
(physicalEntity)	[CatalystActivity:10022872] ubiquitin-ubiquitin ligase activity of p-Pellino:hp-IRAK1:TRAF6 [plasma membrane] [CatalystActivity:10022867] protein kinase activity of TRAF6:hp-IRAK1:Pellino [plasma membrane]
(output)	[Reaction:R-MMU-937034] IRAK1 phosphorylates Pellino [Reaction:R-MMU-937044] Pellino binds hp-IRAK1:TRAF6
(inferredTo)	[Complex:R-HSA-937040] p-Pellino:hp-IRAK1:TRAF6 [plasma membrane] [Complex:R-HSA-937020] TRAF6:hp-IRAK1:Pellino [plasma membrane]