Reactome | Phosphorylated SHC1 recruits SHIP

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Phosphorylated SHC1 recruits SHIP Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10021671
displayName	Phosphorylated SHC1 recruits SHIP
eventOf	[Pathway:R-MMU-912526] Interleukin receptor SHC signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-913424] The SHC1:SHIP1 complex is stabilized by GRB2 - Mus musculus
inferredFrom	[Reaction:R-HSA-913374] Phosphorylated SHC1 recruits SHIP - Homo sapiens
input	[DefinedSet:R-MMU-912534] Interleukin receptor complexes with activated SHC1 [plasma membrane] 4 × [DefinedSet:R-MMU-913467] SHIP1,2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylated SHC1 recruits SHIP
output	[Complex:R-MMU-913393] Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane]
precedingEvent	[Reaction:R-MMU-452100] SHC1 bound to IL2 receptor is phosphorylated - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-913374
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-912526] Interleukin receptor SHC signaling
(precedingEvent)	[Reaction:R-MMU-913424] The SHC1:SHIP1 complex is stabilized by GRB2
(inferredTo)	[Reaction:R-HSA-913374] Phosphorylated SHC1 recruits SHIP

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