Reactome | LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1

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LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 Show undefined attributes

catalystActivity	[CatalystActivity:10087022] glutathione transferase activity of LTC4S trimer [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10087024
displayName	LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1
eventOf	[Pathway:R-MMU-9026762] Biosynthesis of maresin conjugates in tissue regeneration (MCTR) - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9026780] LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 - Homo sapiens
input	[SimpleEntity:R-ALL-9025001] 13(S),14(S)-epoxy-DHA [cytosol] [SimpleEntity:R-ALL-29450] GSH [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + glutathione => (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate
output	[SimpleEntity:R-ALL-9026761] MCTR1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9026780
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9026762] Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
(inferredTo)	[Reaction:R-HSA-9026780] LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1

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