Reactome | Mecp2:Sin3a:Hdac1:Hdac2:Oprm1 gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9017957] Orlic-Milacic, Marija, 2017-08-28
dbId	9017951
displayName	Mecp2:Sin3a:Hdac1:Hdac2:Oprm1 gene [nucleoplasm]
hasComponent	[Complex:R-MMU-9006129] Mecp2:Sin3a:Hdac1:Hdac2 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9017895] Oprm1 gene [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:9017905] Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor [LiteratureReference:9017945] Up-regulation of the mu-opioid receptor gene is mediated through chromatin remodeling and transcriptional factors in differentiated neuronal cells
maxDepth	5
name	Mecp2:Sin3a:Hdac1:Hdac2:Oprm1 gene
negativelyRegulates	[NegativeGeneExpressionRegulation:9017929] Negative gene expression regulation by 'Mecp2:Sin3a:Hdac1:Hdac2:Oprm1 gene [nucleoplasm]'
producedByEvent	[Reaction:R-MMU-9017958] Mecp2:Sin3a complex binds Oprm1 gene promoter - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-9017951

(output)	[Reaction:R-MMU-9017958] Mecp2:Sin3a complex binds Oprm1 gene promoter
(regulator)	[NegativeGeneExpressionRegulation:9017929] Negative gene expression regulation by 'Mecp2:Sin3a:Hdac1:Hdac2:Oprm1 gene [nucleoplasm]'

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