Reactome | NOTCH3 binds YBX1

Schema > Reaction > Entries

NOTCH3 binds YBX1 Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10086352
displayName	NOTCH3 binds YBX1
eventOf	[Pathway:R-MMU-9017802] Noncanonical activation of NOTCH3 - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-MMU-9017817] Gamma-secretase cleaves YBX1:NOTCH3 - Mus musculus
goBiologicalProcess	[GO_BiologicalProcess:20089] Notch signaling pathway
inferredFrom	[Reaction:R-HSA-9017797] NOTCH3 binds YBX1 - Homo sapiens
input	[Complex:R-MMU-157048] NOTCH3 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-9017791] Ybx1 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	NOTCH3 binds YBX1
output	[Complex:R-MMU-9017807] YBX1:NOTCH3 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9017797
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[BlackBoxEvent:R-MMU-9017817] Gamma-secretase cleaves YBX1:NOTCH3
(hasEvent)	[Pathway:R-MMU-9017802] Noncanonical activation of NOTCH3
(inferredTo)	[Reaction:R-HSA-9017797] NOTCH3 binds YBX1

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