Reactome | MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR

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MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR Show undefined attributes

catalystActivity	[CatalystActivity:10085736] sulfurtransferase activity of MPST [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10085738
displayName	MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR
eventOf	[Pathway:R-MMU-1614558] Degradation of cysteine and homocysteine - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN - Mus musculus [BlackBoxEvent:R-MMU-1655879] Thiosulfate can transfer its sulfur atom to glutathione - Mus musculus
inferredFrom	[Reaction:R-HSA-9012721] MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR - Homo sapiens
input	[SimpleEntity:R-ALL-9012592] 3MPYR [mitochondrial matrix] [SimpleEntity:R-ALL-9012724] HSO3- [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR
output	[SimpleEntity:R-ALL-113557] PYR [mitochondrial matrix] [SimpleEntity:R-ALL-1614595] S2O3(2-) [mitochondrial matrix]
precedingEvent	[Reaction:R-MMU-9035484] MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9012721
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1614558] Degradation of cysteine and homocysteine
(precedingEvent)	[Reaction:R-MMU-9013198] TST transfers sulfur from S2O3(2-) to HCN to form HSCN [BlackBoxEvent:R-MMU-1655879] Thiosulfate can transfer its sulfur atom to glutathione
(inferredTo)	[Reaction:R-HSA-9012721] MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR

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