Reactome | p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor

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p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor Show undefined attributes

category	omitted
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10084931
displayName	p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor
eventOf	[Pathway:R-MMU-8984722] Interleukin-35 Signalling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-8984023] p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor - Homo sapiens
input	[Complex:R-MMU-8984010] IL-35:IL27RA:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT3 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor
output	[Complex:R-MMU-8985392] IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-8950418] phospho-Stat1 [cytosol] [EntityWithAccessionedSequence:R-MMU-8982823] phospho-Stat3 [cytosol]
precedingEvent	[BlackBoxEvent:R-MMU-8984014] JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 - Mus musculus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-8984023
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-8984722] Interleukin-35 Signalling
(inferredTo)	[BlackBoxEvent:R-HSA-8984023] p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor

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