Reactome | RUNX1 binds the core TAL1 complex

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RUNX1 binds the core TAL1 complex Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10084194
displayName	RUNX1 binds the core TAL1 complex
eventOf	[Pathway:R-MMU-8939236] RUNX1 regulates transcription of genes involved in differentiation of HSCs - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8956568] RUNX1 binds the core TAL1 complex - Homo sapiens
input	[Complex:R-MMU-8865330] RUNX1:CBFB [nucleoplasm] [Complex:R-MMU-8956524] TAL1 core complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RUNX1 binds the core TAL1 complex
output	[Complex:R-MMU-8956549] RUNX1:CBFB:TAL1 core complex [nucleoplasm]
precedingEvent	[Reaction:R-MMU-8865320] CBFB binds RUNX1 - Mus musculus
regulatedBy	[PositiveRegulation:10084195] Positive regulation by 'CAK [nucleoplasm]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-8956568
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-8939236] RUNX1 regulates transcription of genes involved in differentiation of HSCs
(inferredTo)	[Reaction:R-HSA-8956568] RUNX1 binds the core TAL1 complex

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