Reactome | IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-8950116] IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-447226] Interleukin-12 binds Interleukin-12 receptor - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10018077
displayName	IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane]
hasComponent	[Complex:R-MMU-8950046] IL12RB1:TYK2 [plasma membrane] [Complex:R-MMU-8950039] IL12RB2:JAK2 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8950052] IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane] - Homo sapiens
maxDepth	3
name	IL12RB1:TYK2:IL12RB2:JAK2
producedByEvent	[Reaction:R-MMU-8950128] Interleukin-12 dissociates from Interleukin-12 receptor - Mus musculus [Reaction:R-MMU-447252] IL12RB1:TYK2 binds IL12RB2:JAK2 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-8950052
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-447226] Interleukin-12 binds Interleukin-12 receptor
(output)	[Reaction:R-MMU-8950128] Interleukin-12 dissociates from Interleukin-12 receptor [Reaction:R-MMU-447252] IL12RB1:TYK2 binds IL12RB2:JAK2
(hasComponent)	[Complex:R-MMU-8950116] IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane]
(inferredTo)	[Complex:R-HSA-8950052] IL12RB1:TYK2:IL12RB2:JAK2 [plasma membrane]

Cite Us!