Reactome | ESR1:chaperone complex [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-8939191] ESTG:ESR1:chaperone complex [nucleoplasm] - Mus musculus [Complex:R-MMU-9716887] ESR1:ESR1 agonists [nucleoplasm] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9716947] ESR1 binds ESR1 agonists - Mus musculus [BlackBoxEvent:R-MMU-9032751] Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3 - Mus musculus [Reaction:R-MMU-9716913] ESR1 binds ESR1 antagonists - Mus musculus [Reaction:R-MMU-8939204] ESTG binds ESR1:chaperone complex - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10081105
displayName	ESR1:chaperone complex [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-MMU-446168] ESR1 [nucleoplasm] [Complex:R-MMU-8939186] HSP90 dimer:ATP [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-MMU-5082403] Ptges3 [nucleoplasm] 2 × [CandidateSet:R-MMU-8939175] TPR-containing co-chaperones [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-8939185] ESR1:chaperone complex [nucleoplasm] - Homo sapiens
maxDepth	5
name	ESR1:chaperone complex
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-8939185
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-9716947] ESR1 binds ESR1 agonists [BlackBoxEvent:R-MMU-9032751] Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3 [Reaction:R-MMU-9716913] ESR1 binds ESR1 antagonists [Reaction:R-MMU-8939204] ESTG binds ESR1:chaperone complex
(hasComponent)	[Complex:R-MMU-9716887] ESR1:ESR1 agonists [nucleoplasm] [Complex:R-MMU-9716943] ESR1:ESR1 antagonists [nucleoplasm] [Complex:R-MMU-8939191] ESTG:ESR1:chaperone complex [nucleoplasm]
(inferredTo)	[Complex:R-HSA-8939185] ESR1:chaperone complex [nucleoplasm]