Reactome | Cleaved fibrinogen products bind TLR4:LY96

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10079213
displayName	Cleaved fibrinogen products bind TLR4:LY96
eventOf	[Pathway:R-MMU-5686938] Regulation of TLR by endogenous ligand - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8870678] Cleaved fibrinogen products bind TLR4:LY96 - Homo sapiens
input	[DefinedSet:R-MMU-8870680] FGA, FGB, FGG [extracellular region] [Complex:R-MMU-166050] TLR4:LY96 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Cleaved fibrinogen products bind TLR4:LY96
output	[Complex:R-MMU-8870679] TLR4:LY96:cleaved fibrinogen [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-8870678
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-5686938] Regulation of TLR by endogenous ligand
(inferredTo)	[Reaction:R-HSA-8870678] Cleaved fibrinogen products bind TLR4:LY96

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