Reactome | 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP

Schema > Reaction > Entries

2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP Show undefined attributes

catalystActivity	[CatalystActivity:10077234] 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity of 2xHSD17B8:2xCBR4 [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10077236
displayName	2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP
eventOf	[Pathway:R-MMU-75105] Fatty acyl-CoA biosynthesis - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8862152] 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP - Homo sapiens
input	[SimpleEntity:R-ALL-8862377] 3OA-ACP [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-113600] NADPH [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP a 3-oxoacyl-(ACP) + H(+) + NADPH => a (3R)-hydroxyacyl-(ACP) + NADP(+)
output	[SimpleEntity:R-ALL-8862371] 3HA-ACP [mitochondrial matrix] [SimpleEntity:R-ALL-113563] NADP+ [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-8862152
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-75105] Fatty acyl-CoA biosynthesis
(inferredTo)	[Reaction:R-HSA-8862152] 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP

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