Reactome | Signaling by MST1

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Signaling by MST1 Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10101383
displayName	Signaling by MST1
eventOf	[Pathway:R-MMU-9006934] Signaling by Receptor Tyrosine Kinases - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:184] hepatocyte growth factor receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-MMU-6800198] HPN heterodimer cleaves pro-MST1 to form MST1 dimer - Mus musculus [Reaction:R-MMU-6800315] MST1 binds MST1R - Mus musculus [Reaction:R-MMU-8852522] MST1 dimer:MST1R dimer binds MST1R dimer - Mus musculus [Reaction:R-MMU-8852552] MST1R autophosphorylates - Mus musculus
inferredFrom	[Pathway:R-HSA-8852405] Signaling by MST1 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Signaling by MST1
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-8852405
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9006934] Signaling by Receptor Tyrosine Kinases
(inferredTo)	[Pathway:R-HSA-8852405] Signaling by MST1

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