Reactome | IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10020896] protein tyrosine kinase activity of IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-873821] IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-877269] SOCS-1 and SOCS-3 binds to p-JAK2 - Mus musculus [Reaction:R-MMU-873918] Transphosphorylation of JAK1 - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10020889
displayName	IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane]
hasComponent	[Complex:R-MMU-873823] IFNG dimer [extracellular region] [Complex:R-MMU-873830] IFNGR complex with p-JAK2 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-873811] IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane] - Homo sapiens
maxDepth	4
name	IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2
producedByEvent	[Reaction:R-MMU-873919] Phosphorylation of JAK2 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-873811
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-877269] SOCS-1 and SOCS-3 binds to p-JAK2 [Reaction:R-MMU-873918] Transphosphorylation of JAK1
(physicalEntity)	[CatalystActivity:10020896] protein tyrosine kinase activity of IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane]
(output)	[Reaction:R-MMU-873919] Phosphorylation of JAK2
(hasComponent)	[Complex:R-MMU-873821] IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2:SOCS-1/-3 [plasma membrane]
(inferredTo)	[Complex:R-HSA-873811] IFNG:IFNGR1:JAK1:IFNGR2:p-JAK2 [plasma membrane]

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