Reactome | Butanoyl-CoA+FAD => Crotonoyl-CoA+FADH2

Schema > Reaction > Entries

Butanoyl-CoA+FAD => Crotonoyl-CoA+FADH2 Show undefined attributes

catalystActivity	[CatalystActivity:9990724] acyl-CoA dehydrogenase activity of ACADS tetramer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9990726
displayName	Butanoyl-CoA+FAD => Crotonoyl-CoA+FADH2
eventOf	[Pathway:R-MMU-77352] Beta oxidation of butanoyl-CoA to acetyl-CoA - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF - Mus musculus [Reaction:R-MMU-77314] Crotonoyl-CoA+H2O => (S)-3-Hydroxybutanoyl-CoA - Mus musculus
inferredFrom	[Reaction:R-HSA-77319] Butanoyl-CoA+FAD => Crotonoyl-CoA+FADH2 - Homo sapiens
input	[SimpleEntity:R-ALL-77318] BT-CoA [mitochondrial matrix] [SimpleEntity:R-ALL-113596] FAD [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	Butanoyl-CoA+FAD => Crotonoyl-CoA+FADH2 butanoyl-CoA + FAD + H(+) => (2E)-butenoyl-CoA + FADH2
output	[SimpleEntity:R-ALL-77313] Crotonoyl-CoA [mitochondrial matrix] [SimpleEntity:R-ALL-31649] FADH2 [mitochondrial matrix]
precedingEvent	[Reaction:R-MMU-77321] 3-Oxohexanoyl-CoA+CoA-SH => Butanoyl-CoA + acetyl-CoA - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-77319
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-77352] Beta oxidation of butanoyl-CoA to acetyl-CoA
(precedingEvent)	[Reaction:R-MMU-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF [Reaction:R-MMU-77314] Crotonoyl-CoA+H2O => (S)-3-Hydroxybutanoyl-CoA
(inferredTo)	[Reaction:R-HSA-77319] Butanoyl-CoA+FAD => Crotonoyl-CoA+FADH2

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