Reactome | palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2

Schema > Reaction > Entries

palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2 Show undefined attributes

catalystActivity	[CatalystActivity:9990703] acyl-CoA dehydrogenase activity of ACADVL dimer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9990705
displayName	palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2
eventOf	[Pathway:R-MMU-77305] Beta oxidation of palmitoyl-CoA to myristoyl-CoA - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-77301] trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA - Mus musculus [Reaction:R-MMU-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF - Mus musculus
inferredFrom	[Reaction:R-HSA-77299] palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2 - Homo sapiens
input	[SimpleEntity:R-ALL-113596] FAD [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-77281] PalmCoA [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2 oxidized (electron-transfer flavoprotein) + hexadecanoyl-CoA + H(+) => (2E)-hexadecenoyl-CoA + reduced (electron-transfer flavoprotein)
output	[SimpleEntity:R-ALL-31649] FADH2 [mitochondrial matrix] [SimpleEntity:R-ALL-77284] trans-Hexadec-2-enoyl-CoA [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-77299
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-77305] Beta oxidation of palmitoyl-CoA to myristoyl-CoA
(precedingEvent)	[Reaction:R-MMU-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF [Reaction:R-MMU-77301] trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA
(inferredTo)	[Reaction:R-HSA-77299] palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2

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