Reactome | conversion of 5,6-dihydrouracil to 3-ureidopropionate

Schema > Reaction > Entries

conversion of 5,6-dihydrouracil to 3-ureidopropionate Show undefined attributes

catalystActivity	[CatalystActivity:9988150] dihydropyrimidinase activity of DPYS tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9988152
displayName	conversion of 5,6-dihydrouracil to 3-ureidopropionate
eventOf	[Pathway:R-MMU-73621] Pyrimidine catabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-73591] conversion of 3-ureidopropionate to beta-alanine - Mus musculus
inferredFrom	[Reaction:R-HSA-73589] conversion of 5,6-dihydrouracil to 3-ureidopropionate - Homo sapiens
input	[SimpleEntity:R-ALL-73584] 5,6-Dihydrouracil [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	conversion of 5,6-dihydrouracil to 3-ureidopropionate 5,6-dihydrouracil + H2O => 3-(carbamoylamino)propanoate + H(+)
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73588] UPROP [cytosol]
precedingEvent	[Reaction:R-MMU-73585] reduction of uracil to form dihydrouracil - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-73589
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-73621] Pyrimidine catabolism
(precedingEvent)	[Reaction:R-MMU-73591] conversion of 3-ureidopropionate to beta-alanine
(inferredTo)	[Reaction:R-HSA-73589] conversion of 5,6-dihydrouracil to 3-ureidopropionate

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