Reactome | RFC Heteropentamer [nucleoplasm]

Schema > Complex > Entries

RFC Heteropentamer [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-6790530] (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Mus musculus [Complex:R-MMU-5653772] ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Mus musculus [Complex:R-MMU-5655467] PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] - Mus musculus [Complex:R-MMU-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Mus musculus
consumedByEvent	[Reaction:R-MMU-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Mus musculus [Reaction:R-MMU-5690213] DNA polymerases delta, epsilon or kappa bind the GG-NER site - Mus musculus [Reaction:R-MMU-69053] RFC binding displaces Pol Alpha - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9985532
displayName	RFC Heteropentamer [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-MMU-68435] RFC1 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-68433] RFC2 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-68431] Rfc3 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-68429] RFC4 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-68427] RFC5 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-68436] RFC Heteropentamer [nucleoplasm] - Homo sapiens
maxDepth	2
memberOf	[CandidateSet:R-MMU-9668941] RFC,(CFT18-RFC) [nucleoplasm] - Mus musculus
name	RFC Heteropentamer
producedByEvent	[Reaction:R-MMU-69068] RFC dissociates after sliding clamp formation - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-68436
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasComponent)	[Complex:R-MMU-5655467] PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] [Complex:R-MMU-5653782] PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] [Complex:R-MMU-5653772] ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] [Complex:R-MMU-5653761] DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] [Complex:R-MMU-5653909] MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] [Complex:R-MMU-6790530] (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] [Complex:R-MMU-68437] RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] [Complex:R-MMU-5651997] MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] [Complex:R-MMU-5651799] PCNA:POLD,POLE:RPA:RFC [nucleoplasm]
(input)	[Reaction:R-MMU-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site [Reaction:R-MMU-5690213] DNA polymerases delta, epsilon or kappa bind the GG-NER site [Reaction:R-MMU-69053] RFC binding displaces Pol Alpha
(output)	[Reaction:R-MMU-69068] RFC dissociates after sliding clamp formation
(activeUnit)	[CatalystActivity:9998867] DNA clamp loader activity of RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm]
(hasMember)	[CandidateSet:R-MMU-9668941] RFC,(CFT18-RFC) [nucleoplasm]
(inferredTo)	[Complex:R-HSA-68436] RFC Heteropentamer [nucleoplasm]

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