Reactome | ALDH1A1 oxidises GA to DGA

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ALDH1A1 oxidises GA to DGA Show undefined attributes

catalystActivity	[CatalystActivity:9987324] aldehyde dehydrogenase (NAD+) activity of ALDH1A1 tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10074198
displayName	ALDH1A1 oxidises GA to DGA
eventOf	[Pathway:R-MMU-70350] Fructose catabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-6799495] GLYCTK phosphorylates DGA to 3PDGA - Mus musculus
inferredFrom	[Reaction:R-HSA-6813749] ALDH1A1 oxidises GA to DGA - Homo sapiens
input	[SimpleEntity:R-ALL-30393] GA [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29360] NAD+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ALDH1A1 oxidises GA to DGA D-glyceraldehyde + H2O + NAD(+) => (R)-glycerate + 2 H(+) + NADH
output	[SimpleEntity:R-ALL-6799497] DGA [cytosol] 2 × [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol]
precedingEvent	[Reaction:R-MMU-70342] ALDOB tetramer cleaves Fru-1-P to GA and DHAP - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-6813749
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-70350] Fructose catabolism
(precedingEvent)	[Reaction:R-MMU-6799495] GLYCTK phosphorylates DGA to 3PDGA
(inferredTo)	[Reaction:R-HSA-6813749] ALDH1A1 oxidises GA to DGA

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