Reactome | APAF1 binds AVEN

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10071164
displayName	APAF1 binds AVEN
eventOf	[Pathway:R-MMU-9627069] Regulation of the apoptosome activity - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6805507] APAF1 binds AVEN - Homo sapiens
input	[Complex:R-MMU-9627055] APAF1:ADP [cytosol] [EntityWithAccessionedSequence:R-MMU-6805514] Aven [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	APAF1 binds AVEN
output	[Complex:R-MMU-6805523] APAF1:AVEN [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-6805507
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-9627069] Regulation of the apoptosome activity
(inferredTo)	[Reaction:R-HSA-6805507] APAF1 binds AVEN

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