Reactome | GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC

Schema > Reaction > Entries

GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC Show undefined attributes

catalystActivity	[CatalystActivity:10067304] glycine N-methyltransferase activity of GNMT tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10067306
displayName	GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC
eventOf	[Pathway:R-MMU-389661] Glyoxylate metabolism and glycine degradation - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6798317] GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC - Homo sapiens
input	[SimpleEntity:R-ALL-71284] AdoMet [cytosol] [SimpleEntity:R-ALL-29424] Gly [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC glycine + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + sarcosine
output	[SimpleEntity:R-ALL-71285] AdoHcy [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-5359017] SARC [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-6798317
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-389661] Glyoxylate metabolism and glycine degradation
(inferredTo)	[Reaction:R-HSA-6798317] GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC

Cite Us!