Reactome | 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA

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47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA Show undefined attributes

catalystActivity	[CatalystActivity:10066800] 5'-3' RNA exonuclease activity of XRN2 [nucleoplasm]
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10066806
displayName	47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA
eventOf	[Pathway:R-MMU-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-6791227] 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA - Homo sapiens
input	[Complex:R-MMU-6791184] 47S pre-rRNA:SSU processome [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA
output	[Complex:R-MMU-6791211] 45S pre-rRNA:SSU processome [nucleoplasm]
regulatedBy	[Requirement:10066620] Requirement by 'NOL11 [nucleoplasm]' [Requirement:10066625] Requirement by 'UTPA complex [nucleoplasm]' [PositiveRegulation:10066807] Positive regulation by 'UTPC complex [nucleoplasm]' [Requirement:10066808] Requirement by 'NCL [nucleoplasm]' [Requirement:10066809] Requirement by 'UTP18 [nucleoplasm]' [Requirement:10066336] Requirement by 'SKIV2L2 [nucleoplasm]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-6791227
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-6791226] Major pathway of rRNA processing in the nucleolus and cytosol
(inferredTo)	[BlackBoxEvent:R-HSA-6791227] 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA

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